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Allergen immunotherapy (desensitisation), where indicated and available in line with BSACI guidance and NICE CKS criteria can provide long-term symptom relief without the need for ongoing pharmacological management

The ideal clinical candidate is an adult experiencing symptoms of hormonal decline, such as fatigue, loss of muscle mass, and persistent abdominal fat, who is seeking deeper metabolic optimization through high-purity compounding pharmacy protocols rather than relying on the ineffective quick fixes commonly marketed online

As the obesity epidemic continues to strain healthcare systems globally, the demand for effective pharmacological interventions is only expected to grow

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doi: 10.1210/clinem/dgaf336 19